radioimmunotherapy-based treatment of cancer

Radioimmunotherapy-based treatment of cancer

The principle of cancer immunotherapy includes various methods of manipulations to influence immune responses against tumors in both humans and animals. This advanced technology of hybridoma production provided the necessary skills to efficiently produce highly specific monoclonal antibodies (mAb). Radioactively-tagged antibodies which are applied in radioimmunotherapy (RIT), can target adjacen...

Pretargeted radioimmunotherapy in the treatment of metastatic medullary thyroid cancer

Medullary thyroid carcinoma (mtc) is a rare cancer (less than 8% of all thyroid cancers) that occurs both as a familial and as a sporadic disease. Total thyroidectomy with dissection of the ipsilateral and central lymph nodes, sometimes extended to contralateral dissection, is the primary treatment of hereditary and sporadic mtc alike. after surgery, many patients are cured, especially those wi...

Radioimmunotherapy for colorectal cancer.

Monoclonal antibodies, selected for their ability to recognize and bind tumor-specific antigens, are a promising vehicle for systemic antitumor therapy. Radioimmunotherapy utilizes radioisotopes conjugated to monoclonal antibodies to deliver tumoricidal radiation doses. In the >20 years since radioimmunotherapy began, many obstacles to successful application of this antitumor modality have been...

etiology, significance, diagnosis and treatment of bruxiam

چکیده ندارد.

Breast Cancer: Radioimmunoscintigraphy and Radioimmunotherapy

Intraperitoneal radioimmunotherapy for ovarian cancer.

Twenty-eight patients with assessable residual ovarian cancer after cytoreductive surgery and chemotherapy received intraperitoneal I-131 labelled monoclonal antibodies. There was no response in eight patients with tumour nodules greater than 2 cm, a partial response in two of the 15 patients with tumour nodules less than 2 cm, and a complete response in three of the other five patients with po...